COVID-19’s Biological Politics

If interested, readers can keyword search ‘furin’ at USMB for all of the entries, which we now link to breast cancer and hydroxychloroquine:

May 2021 Russia-China: Furin Re-Education of Macrophages / Breast Cancer Hydroxychloroquine / Nanogold
’....In-vitro studies demonstrated the superiority of furin-triggered aggregated gold nanoparticles delivery system....co-delivery of DOX and HCQ showed much improved chemotherapeutic efficiency to chemoresistant MFC-7/ADR breast tumor.’

In passing, it is possible that a rubella-like virus once raged amongst the thylacoleonids of Australia. If nature were experimenting with double-uterine animals, it would have been extremely difficult for the mother Wakaleo to find food with cataracts, let alone her young escaping from predators.
 
So, we’ll hold onto the rubella-coronavirus links as we find them.

Listing the collaboration of the Report that follows....

Jul 2020 France. Transplacental Transmission of SARS-CoV-2

1. Division of Obstetrics and Gynecology, Antoine Beclere Hospital, Paris Saclay University Hospital, Clamart, France

2. Division of Virology, Paul Brousse Hospital, Paris Saclay University Hospitals, Villejuif, France

3. Division of Pathology, Becetre Hospital, Le Kremlin-Bicetre, France

4. Pathophysiology and Therapeutic Innovation Unit-INSERM U999, Paris, France

’....thrombocytopenia (54 x 10(9)/L), lymphopenia (0.54 x 10(9)L), prolonged APPT (60 s), transaminitis (AST 81 IU/L; ALT 41 IU/L), elevated c-reactive protein (37 mg/L) and ferritin (43 mcg/L) were observed upon admission.
....
Three days after admission a category III-fetal heart rate tracing was observed and therefore category II-cesarean section (i.e., fetal compromise; not immediately life-threatening) was performed....blood and non-bronchoscopic bronchoaveolar lavage fluid were collected for RT-PCR and both were positive for the E and S genes of SARS-CoV-2....On the third day of life, the neonate suddenly presented with irritability, poor feeding, axial hypertonia and opisthonos: cerebrospinal fluid (CSF) was negative for SARS-CoV-2.
....
The neonate presented with neurological manifestations similar to those in adult COVID-19 patients.’
 
The article continues:

’Fig. 1 Tachycardia absent baseline variability, absence of accelerations with recurrent prolonged and late decelerations. These findings are highly suggestive of a pathological category III-fetal heart rate tracing, which is strongly associated with adverse neonatal outcome. This cardiogram was recorded 26 minutes before the cesarean section.
....
A classification for the case definition of SARS-CoV-2 infection in pregnant women, fetuses and neonates has recently been released and we suggest to follow it to characterize cases of potential perinatal SARS-CoV-2 transmission. According to this classification system, a neonatal congenital infection is considered proven if the virus is detected inn amniotic fluid collected prior to the rupture of membranes or in blood drawn early in life, so our case fully qualifies as congenitally-transmitted SARS-CoV-2, while the aforementioned cases would be classified as only possible or even unlikely.’
 
A report from University of New Mexico in 1999 stated no evidence of transplacental hantavirus transmission:

1999
’....No evidence of vertical transmission of Sin Nombre virus was found.’

This 2006 Korean report cites the New Mexican report, but adds a case:
’....In Korea, only 8 cases of HFRS (hemorrhagic fever with renal syndrome) complicating pregnancy (including the present one) have been reported. Gestational age at time of diagnosis ranged from 15-29 weeks, and none of the reported patients showed evidence of abnormal fetal development, distress or pregnancy complication before presentation. Of these 8 cases, the pregnancies did not achieve full-term in three, and it’s interesting that they were all in the early third trimester of pregnancy when they contracted the disease. These three resulted in intrauterine death, preterm delivery but fetal death after birth, and preterm cesarean section, respectively. Among these cases, only one case of transplacental transmission of Hantaan virus was confirmed, both serologically and pathologically. In the other cases, including our case, the presence of transplacental Hantaan remains unknown because the appropriate fetal laboratory tests were not performed.’
 
In comparison to C-19, the hantavirus trajectory is attractive for multiple reasons, not least of which is the geography of the epidemiology when connecting the dots to the symptoms. In that way, an image builds, of the expression of the SARS-CoV-2 mutations that comprise the variants. Future studies will likely further scrutinize such examples as the number of humans in California infected with the California variants B.1.427 & B.1.429 (the latter, more complexity), while linking them to the statistics for those Californians who died after receiving the vaccine. In this way, underlying conditions will link to the genes (and the amino acids [italics]) the virus uses to escape immune surveillance.

For the intriguing placental aspects of hantavirus, we note that it as a Michigan female, though the gender is not mentioned in Nevada:

7 Jun 2021 Michigan: Sin Nombre Hantavirus / Female / Washtenaw County
https://www.michigan.gov/mdhhs/0,5885,7-339–56125—-,00.html


Though the Nevada case mentions no gender.

8 Jun 2021 Reno Gazette
 
The Michigan URL was the weirdist seen in a while. No human should try to transcribe it. Are they (all[italics]) stoned on gonad-effeminizing cannabis over there?
 
There’s practically no speculation extant on the actual amino acid significance of C-19 mutations. We will list these from the “Delta variant.”

New York Times 13 Jun 2021 In China’s Latest Outbreak, Doctors Say the Infected Get Sicker, Faster
’....the dominant variant in Britain....and may infect some people who have received only one of the two doses of COVID-19 vacccine.’

By one estimation, these deletions seem to be acting like an inherited human gene disorder:

Delta Variant Mutations

T19R
G142D
156del
157del
R158G
L452R (both California variants have this mutation)
T478K
D614G (is Fauci’s “mistake”in his video, and links to ebola vaccine)
P681R
D950N
 
#468: Yes, Australia is tomorrow today, and previously they warned about it:

27 Jul 2020 Identify Host Animal Carrying COVID-19 or Risk Future Outbreaks, Says Top Scientist

There are two populations of COVID-19. One of them is evolving in Nature.
 
So at timepoint 3:47 in this suspiciously dramatized video, the reader meets Zheng-Li Shi, the scientist who studied COVID-19’s closest relative from the Mojiang mine, RaTG13:
 
Associated with the Australian Museum (post # 469) is another Australian museum, and may hold the skull of Wakaleo mentioned in post # 457 of this thread, further following the Felidae trajectory via the COVID-19-infected Bronx Tiger previously mentioned (post # 429):

New South Wales: Australian Fossil and Mineral Museum

Wakaleo was a thylacoleonid. Note the markings of a thylacoleonid. It is suggested is that they were once infected by rubivirus-like viruses and coronaviruses:

Thylacoleonidae
 
In post #378 of this thread (27 May 2021), calcium signaling caught the eye for Kawasaki disease, and this was due to recalling some time ago, a certain Wisconsin female who always seemed to be walking with a purpose. First intuition was that the purpose had something to do with calcium metabolism. Over a year later, that suspicion was reinforced today when investigating the Thylacoleonid trajectory. Thylacoleonids may have been predatory for wombats, and as well, may be distantly related. The transfer of viruses can happen in this way, and there is genetic evidence for a human-wombat link to calcium metabolism and the genes of both, as will be shown.

Concerning the uniqueness of the deletions in the Delta variant of COVID-19, we stated in post #467: ‘By one estimation, these deletions seem to be acting like an inherited human gene disorder.’


We note that the Chinese were molesting wombats in Australia, and Australians used to call wombats ‘badgers.’

Aug 2019 Greens Condemn Chinese High Rollers Being Offered Wombat Hunts

We recall the Bronx tiger infected with C-19, and it is the concept of confinement and sedentation that affects calcium metabolism and links tiger-wombat in captivity. The markings of Thylacoleonid may be a sign linking internal genetics in the Felidae (Cats).

2014: Tel Aviv University / Vombatus Congenital Hyperostotic Bone Disease
’....Possible causes for the lesions, including sclerosing bone dysplasia, acquired syndromes causing hyperostosis, and metabolic diseases typical of animals in captivity, are discussed.’

We believe that the Wisconsin female was walking for the exercise that opposes the tendency linked to the captivity-induced hyperostotic symptom, just as in Australian ‘badgers’ or even captive tigers.

Further investigating the calcium metabolism trajectory, a linking deletion in a gene was found, as well as a link to BDNF in addition to COVID-19 vaccines that use an adenovirus vector:

Aug 2006 Japan: ‘Adenovirus Vector Carrying BDNF Gene Prevents Loss of Mouse (twy/twy) Anterior Horn Neurons’
’....mechanical compression in cervical spinal cord of the hyperostotic mouse (twy/twy).’

Jul 2009 University of Connecticut: Mouse Model for Craniometaphyseal Dysplasia / ANKH Gene / Phe377del
’....many typical features of CMD including hyperostosis....’
 
Again from Israel, it was a BDNF restoration report in the snake meat thread, 20 Aug 2020, posts #933-4:

Next, there is the question of which amino acids are involved in the deletions of the Delta variant at positions 156 & 157.
 
We are grateful to the pretty Wisconsin female who linked us to calcium metabolism in wombats (Australian badgers). They suffer from mange, and that investigative trajectory, as will be shown, links to masked palm civets. We are closing in on the natural reservoir of SARS-CoV-2.

Jun 2016 Sarcoptic Mange in Australian Wildlife

With mange and its treatment, we can now confidently link ivermectin’s origin in Japan from soil Streptomyces, to moxidectin (trade name cydectin) in Australia from soil Streptomyces, isolated by an American Cyanamid Company agronomist in the late 1980s:

2021 Vombatus Cydectin Mange Treatment

2015 Masked Palm Civet / Demodex Treatment with Selamectin, Pfizer, Ltd.
’....On histopathology, parasitic dermatitis was observed with the presence of Sarcoptidae mite and Demodex spp.....a notedric mange was thought to be the main problem.’

Next, we link Demodex to a Prefecture not far from ivermectin’s origin in Shizuoka Prefecture:

Feb 2018 Demodex / Saitama Prefecture, Japan
’....Among known species, the mite was similar to D. equi and D. acutipes.’

Immune system compromise in elderly COVID-19 patients compares with integrated retroviral elements into the coronavirus genome, which now links Demodex twice more:

2002 France HIV-1 / Demodex / Ivermectin Response

Feline Immunodeficiency Virus / Demodex
’....a very morphologically heterogeneous population of Demodex mites....’

A Persian cat from India had both Sarcoptes and Demodex:

Persian Cat / India
’....A treatment protocol was initiated that included ivermectin and a bath with shampoo containing selenium sulphide.’

May 2021 SARS-CoV-2 / Demodex / Pyemotes
 
There is a snapshot and a map showing the location of the mine from which COVID-19’s closest relative came, RaTG13:

23 Jan 2021. WHO Focuses on ‘Mine of Death’ for Origin of COVID-19

To the south of Yunnan lies Mengla County, source of the Mengla filovirus, taken from a Rousettus bat, also studied at Wuhan Institute of Virology. Focusing on bat ectoparasites, one of them links not only to the Rousettus species aegyptiacus that is the reservoir of Marburg filovirus, but also the same species of ectoparasite is found in Malaysia, bringing the investigation closer to Mengla County, Yunnan:

Rousettus aegyptiacus (Geoffroy, 1810) / Meristaspis lateralis (Kolenati, 1856)
’....Assiut Governorate, Egypt.’

The same Meristaspis then links to a (Rhinolophid host [italics]) in Malaysia, linking the ‘Mine of Death’ to Rhinolophus affinis for RaTG13:

Malaysia: Meristaspis lateralis / M. macroglossi / Paraperiglischrus rhinolophinus
 
This Madison, Wisconsin, facility, which we have visited, is pretty damn good. They tested for the ability of Eptesicus bats to vector COVID-19, as we reported in post #217 of this thread, though it’s the ectoparasite, not the bat, that we’re interested in:


We’ve already mentioned Demodex.

Jun 2007 Colorado: Demodex

Now it gets really interesting, from a Canadian report:

Mar 2020 Canada: Spinturnix americanus / Lyme Disease / Eptesicus

Note the first Arab POTUS, Obama, living at almost the epicenter of Lyme disease, on Martha’s Vineyard.

This would be months before the ebola outbreak in Guinea, which occurred Dec, 2013:

Mar 2013 Eptesicus / Demodex / Eastern Tennessee

Central Pennsylvania / Spinturnix americanus
’....capture near Bat Church....’

A most delicious report links the closest known relative of SARS-CoV-2:

First Record of Eyndhovenia (Mesostigmata: Gamasina: Spinturnicidae) from Vietnam
’....Between 2018 and 2020, we conducted a series of bat surveys and recorded this genus from intermediate horseshoe bat, Rhinolophus affinis, in Vietnam.’

Rhinolophus affinis is the host to COVID-19’s closest relative, RaTG13, from the Mojiang Copper Mine, Yunnan.
 
Thus there is at least one named ectoparasite, Eyndhovenia, of the bat species that harbored SARS-CoV-2’s closest relative, RaTG13.

13 Jun 2021 New Details on COVID Origins and Wuhan Lab
 
In the video above at timepoint 1:17, Bossert mentions the lack of the civet cat for this SARS outbreak, though the Australian Wakaleo trajectory produced ectoparasite links between civet cats and domestic cats. It is in the video that they briefly mention, that we see and hear Zheng-li Shi (or Shi Zheng-li): “We heard the rumors that claimed our laboratory would have some project blah blah with army blah blah these kinds of rumors....but this is not correct.”

We will shortly begin to compile the military links we have already posted in the now closed snake meat thread, though it was Hua Chunying who accused Ft. Detrick of COVID-19’s origins on 20 Jan 2021, in post #241 of this thread:

Hua Chunying
 
We’ll focus on a post from the snake meat thread, 19 Feb 2020, to link Eco Health Alliance (New York) to Chinese military facilities, including the Rousettus Marburg virus link, to show that the latter can not only be a filovirus reservoir, but a (beta [italics]) coronavirus reservoir as well.

19 Feb 2020 Post # 467
’....:
Jun 2014 R. affinis LYRa11 Complete Genome (submitted 22 Aug 2013)
’Key Laboratory of Jilin Province for Zoonosis Prevention And Control, Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China....Yunnan Institute of Endemic Diseases Control and Prevention, Dali, Yunnan
....
Since 2005, the host range of SARS-like CoVs has extended from Rhinolophus spp. to Chaerephon spp. in China and Hipposideros and Chaerephon spp. in Africa. Most SARS-like CoVs from non-Rhinolophus species show far greater genetic distance to SARS-CoVs than those from Rhinolophus species. This is especially true for viruses from Africa, which share less than 83% full genomic identities with SARS-CoVs.’
(tbc)
 
The connection is that Eco Health Alliance in New York City has co-authored papers with Yunnan Institute of Endemic Diseases in Dali City, Yunnan.

The report in post # 479 shows in Fig. 3 ‘Rousettus bat coronavirus HKU9.’

Tracking HKU9 leads to two reports:

MERS / Rousettus GRP78 Attachment

The second HKU9 abstract links to vaccine vectors used in COVID-19 vaccines:

Feb 2020 Novel Adenovirus in Rousettus leschenaultii
 

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