COVID-19’s Biological Politics

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To link PEDV to sudden death in the host, is also to link PEDV to (reverse zoonosis [italics]), and we have already linked HCoV-229E to the RGD motif of the SARS2 spike:

Ralph S. Baric and Damon J. Deming, 2008
'Several examples of emergent viruses illustrate the coronaviruses' ability to expand their host range. For instance, porcine epidemic diarrhea virus, an economically significant cause of severe swine gastroenteritis in Europe and Asia, is closely related to HCoV-229E and is believed to be the result of transmission from humans to swine.'
(Nidoviruses, Ch. 4 Genetics and Reverse Genetics of Nidoviruses)

Linda J. Saif
'Features of PEDV not seen in TGE (transmissible gastroenteritis) are acute back muscle necrosis and, occasionally, sudden death in finishing and adult pigs.'
(Nidoviruses, Ch. 18 Coronaviruses of Livestock and Poultry)

 

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Ebright is on to a very important topic: antibiotics.

https://twitter.com/R_H_Ebright

 

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On COVID politics, from @Bryce_Nickels Twitter:
Kevin McCarthy is Already Inviting the Next Pandemic Mess

Kevin McCarthy Is Already Inviting the Next Pandemic Mess

The new speaker could help us beat COVID-19 and prepare for future trouble. He’s gearing up to do the opposite.

thedailybeast.com

 

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29 Dec 2022 Japan: ACE2 Decoy

https://biorxiv.org/content/10.1101/2022/12/29.522275v1.full

'....Compared with the original Wuhan strain, Omicron deep mutational scanning (DMS) analysis showed that no single amino acid mutation in the RBD escaped engineered ACE2 decoy....we evaluated the cardiotoxicity....we minimized predictable risk of drug toxicity in the final drug candidate....produced no escape mutants....'

Miles Davis: Decoy

 

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We deliberately chose the original MTV Decoy video because of the Kandinskyesque visuals near the end of the video. The reader can find it at youtube.

 

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Japan: ACE2 Decoy Broadly Neutralizes Omicron

An engineered ACE2 decoy broadly neutralizes Omicron subvariants and shows therapeutic effect in SARS-CoV-2-infected cynomolgus macaques

The Omicron variant continuously evolves under the humoral immune pressure obtained by vaccination and SARS-CoV-2 infection and the resultant Omicron subvariants exhibit further immune evasion and antibody escape. Engineered ACE2 decoy composed of high-affinity ACE2 and IgG1 Fc domain is an...

biorxiv.org

 

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There many versions of Mile Davis's Decoy. Some are awful. Only the MTV original introduces Kandinsky-esque visuals near the end of the video.

 

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RFK Jr's book, The Wuhan Cover-Up, is due out on Valentine's Day. This Australian Whistleblower:

@Jikkyleaks Australian Whistleblower

Everyone is doing their part to help people understand the Covid-19 "fake vaccine" data and shenanigans within our corrupt governments and health officials. I only just discovered @JikkyLeaks last night (apparently the account spent most ...

pennybutler.com

 

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Another important investigative Twitter page:

https://twitter.com/KanekoaTheGreat

 

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@ 1h, McCullough's short video:

https://twitter.com/healthbyjames

'This requires more attention.'

@ 2h, 'This is being suppressed'

https://twitter.com/healthbyjames

This is getting interesting. Stopping the scrolling video (@2h), the reader may note '1p36 deletion.' Yes, this can be expounded upon. It links to Parkinson's PINK1 gene, which is located at 1p36. We have already linked the RGD motif of SARS2 to Parkinson's. (USMB search 'RGD')

 

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So with 1p36, @healthbyjames makes an extremely important connection. We reinforce the connection by noting the RGD motif found on the spike protein of SARS2 and the same motif linking to 1p36:

Nov 2003 University of Texas Anderson Cancer Center / Insulin-Like Growth Factor Protein 2 / RGD Motif

IIp45, an insulin-like growth factor binding protein 2 (IGFBP-2) binding protein, antagonizes IGFBP-2 stimulation of glioma cell invasion - PubMed

Our previous studies have shown that insulin-like growth factor binding protein 2 (IGFBP-2) is frequently overexpressed in the highly invasive glioblastoma multiforme (GBM). By using a yeast two-hybrid system, we identified a gene, invasion inhibitory protein 45 (IIp45), whose protein product...

pubmed.ncbi.nlm.nih.gov

'....1p36....RGD motif....'

 

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Ebright reminds readers about the vote:

https://twitter.com/R_H_Ebright

'@ 57 m....As part of the rules package that passed the House 220-213 on Monday night, the 12-member Select Committee on the Coronavirus Response will be charged with examining the origins of the pandemic, including federal funding for gain-of-function research.'

 

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So with 1p36, @healthbyjames makes an extremely important connection. We reinforce the connection by noting the RGD motif found on the spike protein of SARS2 and the same motif linking to 1p36:

Nov 2003 University of Texas Anderson Cancer Center / Insulin-Like Growth Factor Protein 2 / RGD Motif

IIp45, an insulin-like growth factor binding protein 2 (IGFBP-2) binding protein, antagonizes IGFBP-2 stimulation of glioma cell invasion - PubMed

Our previous studies have shown that insulin-like growth factor binding protein 2 (IGFBP-2) is frequently overexpressed in the highly invasive glioblastoma multiforme (GBM). By using a yeast two-hybrid system, we identified a gene, invasion inhibitory protein 45 (IIp45), whose protein product...

pubmed.ncbi.nlm.nih.gov

'....1p36....RGD motif....'

1p36 above, links to papillomavirus-16-transformed foreskin:

Jul 2006 UC San Francisco / HPV-16-Transformed Foreskin

Molecular cytogenetic characterization of human papillomavirus16-transformed foreskin keratinocyte cell line 16-MT - PubMed

Anogenital cancers are closely associated with human papillomavirus (HPV), and HPV-infected individuals, particularly those with high-grade dysplasias, are at increased risk for cervical and anal cancers. Although genomic instability has been documented in HPV-infected keratinocytes, the full...

pubmed.ncbi.nlm.nih.gov

'....(1qter--->1q25::1p36.1--->1qter)....'

We now link E.C. Holmes's co-author, Yong-Zhen Zhang, to 1p36 for rural Chinese female surveillance of cervical cancer in Yunnan and elsewhere in China. Zhang attended the Kunming Institute of Zoology, which is the zoology counterpart for zoologist E.C. Holmes. This Kunming Institute of Zoology was also involved in bat identification, confirming Rhinolophus affinis for the Mojiang miners (26 Ap 2012) as Fauci was testifying to the US Senate.

Some Yong-Zhen Zhang Publications

1.) 2011 Johns Hopkins

Life-style and genital human papillomavirus in a cross-sectional survey in Shanxi Province, China - PubMed

The HPV prevalence rate was lowest among child bearing women aged 25-34 year. Also, personal hygiene is significantly associated with the HPV infection in this area, regardless of age.

pubmed.ncbi.nlm.nih.gov

2.) Jun 2011

Evaluation of primary HPV-DNA testing in relation to visual inspection methods for cervical cancer screening in rural China: an epidemiologic and cost-effectiveness modelling study - PubMed

This modelled analysis suggests that primary careHPV screening compares favourably to visual inspection screening methodologies in rural China, particularly if used as part of a regular screening program.

pubmed.ncbi.nlm.nih.gov

3.) Jun 2014

https://ncbi.nlm.nih.gov/24642241

The transformative HPV-16/1p36.1 then links to Schwartz-Jampel syndrome for faulty encoding of the perlecan gene:

Schwartz-Jampel Syndrome / Perlecan

Medical Definition of Schwartz-Jampel syndrome

Read medical definition of Schwartz-Jampel syndrome

medicinenet.com

'....mutations in the gene encoding perlecan on chromosome 1p36.1.'

 

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3.) A parallel study of careHPV and Hybrid Capture 2 human papillomavirus DNA testing for cervical cancer screening in rural China - PubMed

 

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So Yong-Zhen Zhang and E.C. Holmes being co-authors of certain papers now link both of them to chromosome 1p36, which is the RGD motif/Parkinson's/PINK1 link:

PINK1

PINK1 - Wikipedia

en.wikipedia.org

'phosphatase and tensin homologue deleted on chromosome 10....PTEN....'

15 Aug 2016 PINK1 is a Negative Regulator of Growth

PINK1 Is a Negative Regulator of Growth and the Warburg Effect in Glioblastoma

These findings offer a mechanistic rationale to attack aggressive brain cancers by reprogramming a critical metabolic pathway that sustains them.

aacrjournals.org

'....transformed using random retroviral insertions....PINK1 is located on chromosome 1p36, a recurrent deleted hotspot for several cancers....'

@Jikkyleaks and other Twitterists have recently mentioned p53, though it's not clear if they've made the RGD connection for Parkinson's or the 1p36 connection to cancer. Dr. Quay shows the RGD motif from the military bat virus, ZC45, on 24 Aug 2022: 'RGDPdeletiondeletiondeletion.'

Parkinson's / RGD Motif

Oxidized/deamidated-ceruloplasmin dysregulates choroid plexus epithelial cells functionality and barrier properties via RGD-recognizing integrin binding - PubMed

Choroid plexus epithelial cells (CPEpiCs) determine the composition of cerebrospinal fluid (CSF) and constitute the blood-CSF barrier (BCSFB), functions that are altered in neurodegenerative diseases. In Parkinson's disease (PD) the pathological environment oxidizes and deamidates the...

pubmed.ncbi.nlm.nih.gov

 

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@8h

https://twitter.com/Jikkyleaks.com

'....What if I told you that you can detect somebody who has received a Pfizer vaccine by PCR? That person is "tagged." '

 

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https://twitter.com/Jikkyleaks

 

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What else could Russians find out about Macron's genome? Macron refused the test.
Putin-Macron

https://twitter.com/JrmeC14

 

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PEDV is the only known coronavirus linked to sudden death in the host (pigs). @5h, Jikky links vaginal arrhythmia:

https://twitter.com/Jikkyleaks

'.....First one to spot it: Symptoms of Vaginal Arrhythmia....'

A genetic link to both sudden death and arrhythmia is Brugada Syndrome caused by a sodium channelopathy:

Brugada / SCN5a

Brugada syndrome: update and future perspectives - PubMed

Brugada syndrome (BrS) is an inherited cardiac disorder, characterised by a typical ECG pattern and an increased risk of arrhythmias and sudden cardiac death (SCD). BrS is a challenging entity, in regard to diagnosis as well as arrhythmia risk prediction and management. Nowadays, asymptomatic...

pubmed.ncbi.nlm.nih.gov

 

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From Brugada syndrome linking SCN5a (post #1,699) to this first, original German article that links SCN5a to tropomyosin. Recalling Brooks Jackson's questioning of Pfizer troponin studies (@theJikky), the link between troponin and tropomyosin is here:

Germany / SCN5a / Mouse Alpha-Tropomyosin / Troponin

Chromosomal localization and genomic cloning of the mouse alpha-tropomyosin gene Tpm-1 - PubMed

In vertebrates, the alpha-tropomyosin gene, Tpm-1, codes for at least 9 tropomyosin isoforms that are expressed by tissue-specific alternative splicing. Using interspecies backcrosses, we have localized Tpm-1 on mouse chromosome 9, cen-Cyp1a2-Tpm-1-Mod-1-Mylc-Scn5a, near the d-se region. The...

pubmed.ncbi.nlm.nih.gov

The reasoning is that, whether mRNA spike or viral spike, if the spike has increased electrical charge, and if SCN5a is a voltage-gated sodium channel, then the coagulative tendency of either mRNA "vaccine" or SARS2 virus itself would interfere with this sodium channel linked to sudden death. Reinforcing this hypothesis is this Russian-Finnish study:

Dec 2022 Russia, Finland / Troponin-Tropomyosin

Impact of Troponin in Cardiomyopathy Development Caused by Mutations in Tropomyosin - PubMed

Tropomyosin (Tpm) mutations cause inherited cardiac diseases such as hypertrophic and dilated cardiomyopathies. We applied various approaches to investigate the role of cardiac troponin (Tn) and especially the troponin T (TnT) in the pathogenic effects of Tpm cardiomyopathy-associated mutations...

pubmed.ncbi.nlm.nih.gov

'....A277V....K15N....'

The first mutation, A277V is an early-onset Alzheimer's mutation while the second, K15N is the reverse of Omicron mutation N969K, which is the first SARS2 specifically vaccine-linked mutation to arise.