MindWars
Diamond Member
- Oct 14, 2016
- 42,227
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- #21
When your a fkn moron who has NO INFORMATION you vaccinate :
Human Cell Strains in Vaccine Development
Stanley Plotkin
Stanley Plotkin
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Animals have been used in the industrialized production of human vaccines since vaccine farms were established to harvest cowpox virus from calves in the late 1800s. From that point, and through the first half of the 20th century, most vaccines would continue to be developed with the use of animals, either by growing pathogens in live animals or by using animal cells.
Although many vaccines and anti-toxin products were successfully developed this way, using animals in vaccine development – particularly live animals – is not ideal. Research animals are costly and require extensive monitoring, both to maintain their health and to ensure the continued viability of the research. They may be carrying other bacteria or viruses that could contaminate the eventual vaccine, as with polio vaccines from the mid 20th century that were made with
Human Cell Strains in Vaccine Development | History of Vaccines
WHEN YOUR A FKN UNINFORMED IDIOT WHO DOESN'T KNOW................
Current Vaccines Developed Using Human Cell Strains
Two main human cell strains have been used to develop currently available vaccines, in each case with the original fetal cells in question obtained in the 1960s. The WI-38 cell strain was developed in 1962 in the United States, and the MRC-5 cell strain (also started with fetal lung cells) was developed, using Hayflick's technology, in 1970 at the Medical Research Center in the United Kingdom. It should be noted that Hayflick's methods involved establishing a huge bank of WI-38 and MRC-5 cells that, while not capable of infinitely replicating like immortal cell lines, will serve vaccine production needs for several decades in the future.
The vaccines below were developed using either the WI-38 or the MRC-5 cell strains.
Human Cell Strains in Vaccine Development | History of Vaccines
Human Cell Strains in Vaccine Development
Stanley Plotkin
Stanley Plotkin
" style="box-sizing: border-box; display: inline-block; width: 75px; margin-right: 3px; margin-bottom: 6px;">
Animals have been used in the industrialized production of human vaccines since vaccine farms were established to harvest cowpox virus from calves in the late 1800s. From that point, and through the first half of the 20th century, most vaccines would continue to be developed with the use of animals, either by growing pathogens in live animals or by using animal cells.
Although many vaccines and anti-toxin products were successfully developed this way, using animals in vaccine development – particularly live animals – is not ideal. Research animals are costly and require extensive monitoring, both to maintain their health and to ensure the continued viability of the research. They may be carrying other bacteria or viruses that could contaminate the eventual vaccine, as with polio vaccines from the mid 20th century that were made with
Human Cell Strains in Vaccine Development | History of Vaccines
WHEN YOUR A FKN UNINFORMED IDIOT WHO DOESN'T KNOW................
Current Vaccines Developed Using Human Cell Strains
Two main human cell strains have been used to develop currently available vaccines, in each case with the original fetal cells in question obtained in the 1960s. The WI-38 cell strain was developed in 1962 in the United States, and the MRC-5 cell strain (also started with fetal lung cells) was developed, using Hayflick's technology, in 1970 at the Medical Research Center in the United Kingdom. It should be noted that Hayflick's methods involved establishing a huge bank of WI-38 and MRC-5 cells that, while not capable of infinitely replicating like immortal cell lines, will serve vaccine production needs for several decades in the future.
The vaccines below were developed using either the WI-38 or the MRC-5 cell strains.
- Hepatitis A vaccines [VAQTA/Merck, Havrix/GlaxoSmithKline, and part of Twinrix/GlaxoSmithKline]
- Rubella vaccine [MERUVAX II/Merck, part of MMR II/Merck, and ProQuad/Merck]
Human Cell Strains in Vaccine Development | History of Vaccines
