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Snake Meat......source of chinese virus
- Thread starter MacTheKnife
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Avian Flu Talk caught it 18 minutes ago, msm caught it 11 minutes ago:
First Death Washington State
France Cancels Paris Race; Xi Scraps Japan Visit: Virus Update
First Death Washington State
France Cancels Paris Race; Xi Scraps Japan Visit: Virus Update
We establish transmission of IBV to monkeys in 1954:
IBV / Cynomolgus Monkey
Transmission of the avian infectious bronchitis virus to the cynomolgus monkey. - PubMed - NCBI
IBV / Cynomolgus Monkey
Transmission of the avian infectious bronchitis virus to the cynomolgus monkey. - PubMed - NCBI
Avian Flu Talk thread "Wa Scientist Estimates Outbreak in Hundreds": '....the team at SeattleFluStudy have sequenced the genome of COVID-19 community case reported yesterday from Snohomish County, Wa and have posted the sequence publicly to GISAID.org. There are some enormous implications here.'
First COVID-19 U.S. Nursing Home
First Covid-19 outbreak in a U.S. nursing home raises concerns spread-in-nursing-homes/
'....Kirkland, Wa....'
First Covid-19 outbreak in a U.S. nursing home raises concerns spread-in-nursing-homes/
'....Kirkland, Wa....'
Here's the catch in post #565: the published genome of the Snohomish COVID-19 case immediately becomes esoterica, although the entire U.S. population is at risk, especially in Washington State (as per post # 554).
gisaid.org/registration/register/
gisaid.org/registration/register/
This is a descent shot of the potential COVID-19 reservoir in Washington state, which should be protected for important scientific reasons:
Painted Turtle
Painted Turtle
Painted Turtle
Painted Turtle
The Israeli COVID-19 vaccine is based on IBV.
'In 1937, Beaudette and Hudson found that the agent was capable of propagation in chicken embryos....the infectious bronchitis virus used in this study was obtained from Dr. F.R. Beaudette of the New Jersey Agricultural Experiment Station....Two young cynomolgus monkeys (Macaca cynomolgus)....eight days postinoculation one of the monkeys evidenced symptoms of respiratory involvement. The animal developed a nasal discharge and a cough, the eyes became filled with exudate and appeared very swollen and respiration became laborious....on the 10th day became prostrate and died during the night. The second inoculated monkey was held for a 21-day observation period and remained normal throughout. Autopsy of the dead monkey revealed a small area of consolidation (about 1cm diameter) in the lower right lung....and thereby fulfilled Koch's postulates.'
'In 1937, Beaudette and Hudson found that the agent was capable of propagation in chicken embryos....the infectious bronchitis virus used in this study was obtained from Dr. F.R. Beaudette of the New Jersey Agricultural Experiment Station....Two young cynomolgus monkeys (Macaca cynomolgus)....eight days postinoculation one of the monkeys evidenced symptoms of respiratory involvement. The animal developed a nasal discharge and a cough, the eyes became filled with exudate and appeared very swollen and respiration became laborious....on the 10th day became prostrate and died during the night. The second inoculated monkey was held for a 21-day observation period and remained normal throughout. Autopsy of the dead monkey revealed a small area of consolidation (about 1cm diameter) in the lower right lung....and thereby fulfilled Koch's postulates.'
The stump-tailed macaque (Macaca arctoides) also occurs in Yunnan, home of the bat SARS-like RaTG13, mentioned previously as closest to COVID-19. Thus, if Thai anti-HIV-1 meds were successful in treating COVID-19 infection, M. arctoides indeed links to HIV-2, which many consider an older virus than HIV-1.
On p. 842 of Hooper's The River: A Journey to the Source of HIV and AIDS, a figure shows 'Unrooted, Neighbor-Joining Phylogenetic Tree Featuring the Complete Genomes of the Primate Immunodeficiency Viruses, May 1999.' STMM83293 SIV from stump-tailed macaque is shown on the branch for HIV-2, Sooty Mangabey....Source: Prepared specially for this book by Brian Foley, PhD., HIV Database, Theoretical Biology and Physics Group, Group T-10, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. The alignment from which this tree was constructed is available at
http://hiv-web.lanl.
.'
Foley is co-author of the latest COVID-19 report from Wuhan (post #543), and supports Israeli use of IBV-based COVID-19 vaccine.
On p. 842 of Hooper's The River: A Journey to the Source of HIV and AIDS, a figure shows 'Unrooted, Neighbor-Joining Phylogenetic Tree Featuring the Complete Genomes of the Primate Immunodeficiency Viruses, May 1999.' STMM83293 SIV from stump-tailed macaque is shown on the branch for HIV-2, Sooty Mangabey....Source: Prepared specially for this book by Brian Foley, PhD., HIV Database, Theoretical Biology and Physics Group, Group T-10, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. The alignment from which this tree was constructed is available at
http://hiv-web.lanl.
.'
Foley is co-author of the latest COVID-19 report from Wuhan (post #543), and supports Israeli use of IBV-based COVID-19 vaccine.
The report states that it greatly improved, but did not cure, COVID-19 infection:
17 Feb 2020 Did Thai Doctors Cure Coronavirus with an Anti-HIV Drug in 48 Hours?
Thai doctors say their treatment helped a coronavirus patient recover, but it was not a 'cure'
17 Feb 2020 Did Thai Doctors Cure Coronavirus with an Anti-HIV Drug in 48 Hours?
Thai doctors say their treatment helped a coronavirus patient recover, but it was not a 'cure'
In Praise of the American Redneck: Neither Trump Nor Pence Is Clued-Up
("No Einstein, Alabama Rednecks Are Reacting Quite Appropriately to COVID-19 Quarantines")
To prove this is so, and to prove it is the transmissibility that is of concern, we follow the macaque trajectory for HIV-2:
SIV / Stump-Tailed Macaque
SIV from stump-tailed macaques: molecular characterization of a highly transmissible primate lentivirus. - PubMed - NCBI
'....is unusual in that it has been associated with outbreaks of infection characterized by aggressive spread within within stump-tailed macaque colonies at two separate primate centers in the United States....SIV was introduced into North American macaques by way of cross-species transmission. A strong candidate for the source of transmission has emerged from genetic analysis of SIVs from West African sooty mangabeys....Since the original isolation of SIVmac from rhesus (Macaca mulatta) and cynomolgus (M. fascicularis) macaques at the New England Regional Primate Research Center in 1985, SIV has been recovered at the Washington Regional Primate Research Center....SIVmne was isolated from pig-tailed macaque (M. nemestrina) that died of lymphoma in 1982. Similarly, at the California Regional Primate Research Center, SIVstm was recovered from a stump-tailed macaque (M. arctoides). Interestingly, this macaque had died during an epidemic of lymphoma and opportunistic infections in the 1970s at the California center.
....
More recently, SIVstm has been associated with a similar outbreak in a colony of M. arctoides at the Yerkes Regional Primate Research Center....Thus, the observed genetic variation among the different macaque isolates might merely reflect genetic variation in the imported feral sooty mangabey population. A second possibility is that all SIV infections in the United States originated from a single source and that further transmission occurred in a fashion similar to the recent example at Yerkes. In this case, genetic variation among the macaque isolates might represent the result of 20 or more years of viral replication in different species of macaques in captivity. Finally, it is possible that a combination of the two hypotheses occurred and that multiple transmissions from several sources have taken place over the years. The unusual episodic communicability of this virus suggests that it may differ significantly from those of the other members of this group.'
Furthermore, the doubled incubation time of HIV-2 as compared with HIV-1 may link to the increased incubation time and lack of symptoms in COVID-19 infection.
("No Einstein, Alabama Rednecks Are Reacting Quite Appropriately to COVID-19 Quarantines")
To prove this is so, and to prove it is the transmissibility that is of concern, we follow the macaque trajectory for HIV-2:
SIV / Stump-Tailed Macaque
SIV from stump-tailed macaques: molecular characterization of a highly transmissible primate lentivirus. - PubMed - NCBI
'....is unusual in that it has been associated with outbreaks of infection characterized by aggressive spread within within stump-tailed macaque colonies at two separate primate centers in the United States....SIV was introduced into North American macaques by way of cross-species transmission. A strong candidate for the source of transmission has emerged from genetic analysis of SIVs from West African sooty mangabeys....Since the original isolation of SIVmac from rhesus (Macaca mulatta) and cynomolgus (M. fascicularis) macaques at the New England Regional Primate Research Center in 1985, SIV has been recovered at the Washington Regional Primate Research Center....SIVmne was isolated from pig-tailed macaque (M. nemestrina) that died of lymphoma in 1982. Similarly, at the California Regional Primate Research Center, SIVstm was recovered from a stump-tailed macaque (M. arctoides). Interestingly, this macaque had died during an epidemic of lymphoma and opportunistic infections in the 1970s at the California center.
....
More recently, SIVstm has been associated with a similar outbreak in a colony of M. arctoides at the Yerkes Regional Primate Research Center....Thus, the observed genetic variation among the different macaque isolates might merely reflect genetic variation in the imported feral sooty mangabey population. A second possibility is that all SIV infections in the United States originated from a single source and that further transmission occurred in a fashion similar to the recent example at Yerkes. In this case, genetic variation among the macaque isolates might represent the result of 20 or more years of viral replication in different species of macaques in captivity. Finally, it is possible that a combination of the two hypotheses occurred and that multiple transmissions from several sources have taken place over the years. The unusual episodic communicability of this virus suggests that it may differ significantly from those of the other members of this group.'
Furthermore, the doubled incubation time of HIV-2 as compared with HIV-1 may link to the increased incubation time and lack of symptoms in COVID-19 infection.
Apparently then, the pig-tailed macaque was in Seattle and the stump-tailed macaque was in California, although the Washington state location documents Simian T-cell leukemia virus and Maccacine herpesvirus 1 (B virus) on their webpage. Thus, the gallid herpes 1 virus mentioned in this thread links to maccacine herpes (see post #560 for infectious laryngotracheitis in a painted turtle, Toronto Zoo).
More on community transmission, 1 Mar 2020:
https://usatoday.com/story/news/nat...us-hundreds-may-be-infected-washington-state/
Lymphoma was mentioned in post #498 for lopinavir, which now links the macaques. Thai doctors used oseltamivir, lopinavir and ritonavir against COVID-19, the former being an anti-influenza med. There are no links at Pubmed for oseltamivir and HIV-2. There are 31 refs for lopinavir, vs 57 refs for ritonavir, for HIV-2.
https://usatoday.com/story/news/nat...us-hundreds-may-be-infected-washington-state/
Lymphoma was mentioned in post #498 for lopinavir, which now links the macaques. Thai doctors used oseltamivir, lopinavir and ritonavir against COVID-19, the former being an anti-influenza med. There are no links at Pubmed for oseltamivir and HIV-2. There are 31 refs for lopinavir, vs 57 refs for ritonavir, for HIV-2.
Currently, South Korea seeks coronavirus murder charges:
2 Mar 2020
South Korea seeks coronavirus murder charges, over 3,000 dead worldwide
2 Mar 2020
South Korea seeks coronavirus murder charges, over 3,000 dead worldwide
From AFT 7 minutes ago, FEMA via NBC, a reliable news source:
FEMA preparing for possible coronavirus emergency declaration
FEMA preparing for possible coronavirus emergency declaration
Avian Flu Talk thread, "Pandemic Money Scam"....What will stuff the economy is if people start to modify their behaviour. For example, we stop going to the cinema or eating out, we stop spending Saturdays at the mall. If we all stay home and watch Netflix, the economy will stall. This is why the WHO won't declare a pandemic, and why Trump amongst others keeps playing it down. They want people to behave as normal.'
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