munkle
Diamond Member
- Dec 18, 2012
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This looks like a game changer. They weren't thinking of doing it or getting close to doing it. They did it. Wonder where it is now?
coronanews123.wordpress.com
The lead scientist in the research, UW-Madison Prof. Yoshihiro Kawaoka, known in science circles as a “star in the flu world,” was given a $2 million grant in 2019 by the Gates Foundation. In 2009, Prof. Kawaoka received a $9.5 million grant from Gates for bird flu research which would, according to a UW press release, would study:
“viral proteins that allow avian [bird] influenza viruses to bind to human receptors or facilitate efficient replication in human cells.”
The 2008 research uncovered by IceAgeFarmer is entitled “Genes That Made 1918 Flu Lethal Isolated.” A portion of the research paper follows. As instances of Bird Flu continue to be played up in the media, parallel announcements of a remarkably quickly developed Bird Flu vaccine indicate a renewed push for mandatory vaccinations, digital vaccine passports, and renewed trampling on basic rights and civil liberties.
“By mixing and matching a contemporary flu virus with the “Spanish flu” — a virus that killed between 20 and 50 million people 90 years ago in history’s most devastating outbreak of infectious disease — researchers have identified a set of three genes that helped underpin the extraordinary virulence of the 1918 virus.
Writing December 29 in the Proceedings of the National Academy of Sciences, a team led by University of Wisconsin-Madison virologists Yoshihiro Kawaoka and Tokiko Watanabe identifies genes that gave the 1918 virus the capacity to reproduce in lung tissue, a hallmark of the pathogen that claimed more lives than all the battles of World War I combined….
To find the gene or genes that enabled the virus to invade the lungs, Kawaoka and his group blended genetic elements from the 1918 flu virus with those of a currently circulating avian influenza virus and tested the variants on ferrets, an animal that mimics human flu infection.
For the most part, substituting single genes from the 1918 virus onto the template of a much more benign contemporary virus yielded agents that could only replicate in the upper respiratory tract. One exception, however, included a complex of three genes that, acting in concert with another key gene, allowed the virus to efficiently colonize lung cells and make RNA polymerase, a protein necessary for the virus to reproduce.
“The RNA polymerase is used to make new copies of the virus,” Kawaoka explains. Without the protein, the virus is unable to make new virus particles and spread infection to nearby cells.
In the late 1990s, scientists were able to recover genes from the 1918 virus by looking in the preserved lung tissue of some of the pandemic’s victims. Using the relic genes, Kawaoka’s group was able to generate viruses that carry different combinations of the 1918 virus and modern seasonal influenza virus.
When tested, most of the hybrid viruses only infected the nasal passages of ferrets and didn’t cause pneumonia. But one did infect the lungs, and it carried the RNA polymerase genes from the 1918 virus that allowed the virus to make the key step of synthesizing its proteins.
In 2004, Kawaoka and his team identified another key gene from the 1918 virus that enhanced the pathogen’s virulence in mice. That gene makes hemagglutinin, a protein found on the surface of the virus and that confers on viral particles the ability to attach to host cells.
“Here, I think we are talking about another mechanism,” Kawaoka says. The RNA polymerase is used to make copies of the virus once it has entered a host cell. The role of hemagglutinin is to help the virus gain access to cells.””
In May 2024 former CDC Director Dr. Robert Redfield sounded the alarm on renewed “gain-of-function” research, specifically regarding Bird Flu. Redfield said:
“I think it puts our world at great risk. We have a risk of natural spillover, but there is a species barrier. I’m obviously most worried about Bird Flu. Right now, it takes five amino acid change for it to be effectively infecting humans. That’s a pretty heavy species barrier, but this virus is already now in 26 mammal species, as you saw most recently in cattle. But in the laboratory, I could make it highly infectious for humans in months...that’s the real biosecurity threat that these university labs are doing bio-experiments that are INTENTIONALLY modifying viruses – and Bird Flu I think is going to be the cause of the great pandemic.”
In February 2024, US Senator Joni Ernst wrote a letter to USDA Secretary Tom Vilsack demanding to know why the USDA is “funding of a collaboration with a Chinese Communist Party-linked researcher involving dangerous bird flu experiments.”
Insane Bill Gates-Funded Professor Has Combined Bird Flu With Deadly Spanish Flu in Gain-of-Function Research
As mainstream media jarringly reverses its 3-year long contention and reportage that the COVID vaccines are “safe and effective,” now acknowledging a study which would almost certainly …
coronanews123.wordpress.com
The lead scientist in the research, UW-Madison Prof. Yoshihiro Kawaoka, known in science circles as a “star in the flu world,” was given a $2 million grant in 2019 by the Gates Foundation. In 2009, Prof. Kawaoka received a $9.5 million grant from Gates for bird flu research which would, according to a UW press release, would study:
“viral proteins that allow avian [bird] influenza viruses to bind to human receptors or facilitate efficient replication in human cells.”
The 2008 research uncovered by IceAgeFarmer is entitled “Genes That Made 1918 Flu Lethal Isolated.” A portion of the research paper follows. As instances of Bird Flu continue to be played up in the media, parallel announcements of a remarkably quickly developed Bird Flu vaccine indicate a renewed push for mandatory vaccinations, digital vaccine passports, and renewed trampling on basic rights and civil liberties.
“By mixing and matching a contemporary flu virus with the “Spanish flu” — a virus that killed between 20 and 50 million people 90 years ago in history’s most devastating outbreak of infectious disease — researchers have identified a set of three genes that helped underpin the extraordinary virulence of the 1918 virus.
Writing December 29 in the Proceedings of the National Academy of Sciences, a team led by University of Wisconsin-Madison virologists Yoshihiro Kawaoka and Tokiko Watanabe identifies genes that gave the 1918 virus the capacity to reproduce in lung tissue, a hallmark of the pathogen that claimed more lives than all the battles of World War I combined….
To find the gene or genes that enabled the virus to invade the lungs, Kawaoka and his group blended genetic elements from the 1918 flu virus with those of a currently circulating avian influenza virus and tested the variants on ferrets, an animal that mimics human flu infection.
For the most part, substituting single genes from the 1918 virus onto the template of a much more benign contemporary virus yielded agents that could only replicate in the upper respiratory tract. One exception, however, included a complex of three genes that, acting in concert with another key gene, allowed the virus to efficiently colonize lung cells and make RNA polymerase, a protein necessary for the virus to reproduce.
“The RNA polymerase is used to make new copies of the virus,” Kawaoka explains. Without the protein, the virus is unable to make new virus particles and spread infection to nearby cells.
In the late 1990s, scientists were able to recover genes from the 1918 virus by looking in the preserved lung tissue of some of the pandemic’s victims. Using the relic genes, Kawaoka’s group was able to generate viruses that carry different combinations of the 1918 virus and modern seasonal influenza virus.
When tested, most of the hybrid viruses only infected the nasal passages of ferrets and didn’t cause pneumonia. But one did infect the lungs, and it carried the RNA polymerase genes from the 1918 virus that allowed the virus to make the key step of synthesizing its proteins.
In 2004, Kawaoka and his team identified another key gene from the 1918 virus that enhanced the pathogen’s virulence in mice. That gene makes hemagglutinin, a protein found on the surface of the virus and that confers on viral particles the ability to attach to host cells.
“Here, I think we are talking about another mechanism,” Kawaoka says. The RNA polymerase is used to make copies of the virus once it has entered a host cell. The role of hemagglutinin is to help the virus gain access to cells.””
In May 2024 former CDC Director Dr. Robert Redfield sounded the alarm on renewed “gain-of-function” research, specifically regarding Bird Flu. Redfield said:
“I think it puts our world at great risk. We have a risk of natural spillover, but there is a species barrier. I’m obviously most worried about Bird Flu. Right now, it takes five amino acid change for it to be effectively infecting humans. That’s a pretty heavy species barrier, but this virus is already now in 26 mammal species, as you saw most recently in cattle. But in the laboratory, I could make it highly infectious for humans in months...that’s the real biosecurity threat that these university labs are doing bio-experiments that are INTENTIONALLY modifying viruses – and Bird Flu I think is going to be the cause of the great pandemic.”
In February 2024, US Senator Joni Ernst wrote a letter to USDA Secretary Tom Vilsack demanding to know why the USDA is “funding of a collaboration with a Chinese Communist Party-linked researcher involving dangerous bird flu experiments.”
