Donald said 30 years however -- he even messed up that number.This question should bring quite variety of responses. Lots of issues are out there, and quite a few were covered (although I would say insufficiently).
My choice for the Most Important Point Made is that Hillary Clinton has been part of the federal government for 20 years, and look at the mess that we have. Back in the early 90s as First Lady, she helped author NAFTA, the worst destruction of US jobs in our history. Simultaneously, and all through her 20 years, she supported DOMESTIC outsourcing (AKA immigration), and still does, taking millions of jobs away from Americans, reducing wages, robbing US businesses of (currently) $133 Billion in sales (due to remittances), massive tax revenue losses to welfare, bringing additional crime and foreign diseases into the country, and a long list of other harms.
As Sect of State in 2009-2013, , with a Muslim Brotherhood close aide, (Huma Abedin), the US govt went through a period of amazing friendship with the Muslim Brotherhood, an organization sworn to destroy America, and all of Western civilization. Those resulted in a long list of policies that were pro- Muslim Brotherhood, and anti USA.
Also during this time, in 2011, US troops were removed from Iraq, opening up the vacuum that allowed ISIS to move in. Not taking the Iraqi oil, allowed ISIS to quickly grow and strengthen, into what is now the worst threat (nuclear and EMP) that America has ever faced. Making matters worse, she now wants to allow in hundreds of thousands of immigrants from the Middle East, which is sure to have the ISIS "Trojan Horse" among them (a point that Trump badly needed to make and strangely didn't).
Donald can't seem to keep his numbers straight.
30 years ago was 1986 -- Hillary was still in private law practice.
If Trump had said 20 years that would have made more sense but he only stumbled on this as well.
The actual truth would be 23 years -- with Hillary's first attempt at ACA.
23 does not round to 30 so Trump has no excuse for his screw up.