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Cancer researchers dream of the day they can force tumor cells to morph back to the normal cells they once were. Now, researchers on Mayo Clinic's Florida campus have discovered a way to potentially reprogram cancer cells back to normalcy.
Scientists claim to have discovered the first new human prion in almost 50 years. Prions are misfolded proteins that make copies of themselves by inducing others to misfold. By so doing, they multiply and cause disease. The resulting illness in this case is multiple system atrophy (MSA), a neurodegenerative disease similar to Parkinson's. The study, published August 31 in Proceedings of the National Academy of Sciences, adds weight to the idea that many neurodegenerative diseases are caused by prions.
We've previously heard about wound dressings that kill bacteria, but now researchers at Britain's Swinburne University of Technology are taking a different approach. They're creating a dressing material that attracts bacteria out from within the wound, so that the material and the microbes can then just be pulled off and discarded.
Rutgers engineers have developed a breakthrough device that can significantly reduce the cost of sophisticated lab tests for medical disorders and diseases, such as HIV, Lyme disease and syphilis.
The largest nationwide clinical trial to study high-dose resveratrol long-term in people with mild to moderate Alzheimer's disease found that a biomarker that declines when the disease progresses was stabilized in people ...
Genetics researchers from Case Western Reserve School of Medicine have identified a novel long non-coding RNA (lncRNA), dubbed DACOR1, that has the potential to stymie the growth of tumor cells in the second-most deadly form
A Red Flag for a Neurodegenerative Disease That May Be Transmissible
Animal experiments show how a just-discovered prion triggers a rare Parkinson’s-like disease
By Simon Makin | September 1, 2015
Scientists claim to have discovered the first new human prion in almost 50 years. Prions are misfolded proteins that make copies of themselves by inducing others to misfold. By so doing, they multiply and cause disease. The resulting illness in this case is multiple system atrophy (MSA), a neurodegenerative disease similar to Parkinson's. The study, published August 31 in Proceedings of the National Academy of Sciences, adds weight to the idea that many neurodegenerative diseases are caused by prions.
A Red Flag for a Neurodegenerative Disease That May Be Transmissible
A mechanical hand utilizing DARPA-developed neural technologies has become the first to allow a paralyzed patient to feel physical sensations through a prosthesis. The 28 year-old test subject was able to determine which mechanical finger was being touched whilst blindfolded, with total accuracy.
A recently identified molecule produced by skeletal muscle in response to exercise, has been shown to increase bone mass, according to a collaborative study between researchers at the Mount Sinai Bone Program, Icahn School ...
Scientists have identified a gene - FOXC1 - that, if switched on, causes more aggressive cancer in a fifth of acute myeloid leukaemia (AML) patients, according to a Cancer Research UK study published in the journal Cancer ...
Scientists representing the Stanford University School of Medicine along with their colleagues have discovered a way of regenerating damaged heart muscles by delivering a protein to them by means of a bioengineered patch carrying a protein called Fstl1.
Pilar Ruiz-Lozano, who teaches pediatrics at Stanford, said that this finding will give birth to a revolutionary treatment. She added that right now there’s not a single effective treatment for reversing heart-attack induced scarring in heart. Ruiz-Lozano is the senior author of the study; the other experts to share the study’s authorship are University of California, San Diego’s postdoctoral scholar Ke Wei and Stanford’s postdoctoral scholar in cardiology Vahid Serpooshan.
(Medical Xpress)—A particular kind of genetic interaction called synthetic dosage lethality (SDL) is a promising avenue for future cancer treatment, according to a study reported in the Proceedings of the National Academy
Scientists at Trinity College Dublin have shed light on a fundamental mechanism underlying the development of Alzheimer's disease, which could lead to new forms of therapy for those living with the condition.
A national team of researchers has developed a first-of-its-kind, 3D-printed guide that helps regrow both the sensory and motor functions of complex nerves after injury. The groundbreaking research has the potential to help
Targeting gene interactions to kill tumor cells
(Medical Xpress)—A particular kind of genetic interaction called synthetic dosage lethality (SDL) is a promising avenue for future cancer treatment, according to a study reported in the Proceedings of the National Academy
Team reports major breakthrough in understanding Alzheimer's disease
Scientists at Trinity College Dublin have shed light on a fundamental mechanism underlying the development of Alzheimer's disease, which could lead to new forms of therapy for those living with the condition.
3-D printed guide helps regrow complex nerves after injury
A national team of researchers has developed a first-of-its-kind, 3D-printed guide that helps regrow both the sensory and motor functions of complex nerves after injury. The groundbreaking research has the potential to help
Our bodies have developed a particularly unforgiving immune response when a threat is posed to our lungs. This is great for warding off infections and illness, though is something of a double-edged sword regarding transplants, with the recipient's body often perceiving the incoming organ as a threat and seeking to destroy it. But a new approach promises to boost the success rate of such procedures, by both repairing unhealthy donor lungs that wouldn't otherwise make the grade and reducing the chances of rejection once it is implanted.
Like scratchy-sounding old radio dials that interfere with reception, circuits in the brain that grow noisier over time may be responsible for ways in which we slow mentally as we grow old, according to the results of new ..
(Medical Xpress)—A team of researchers affiliated with several institutions in Japan has succeeded in growing kidneys from stem cells that worked as they were supposed to after being transplanted into rats and pigs.
Liquid crystals are familiar to most of us as the somewhat humdrum stuff used to make computer displays and TVs. Even for scientists, it has not been easy to find other ways of using them.
(Phys.org)—In the past, geneticists focused primarily on the evolution of genes in order to trace the relationships between species. More recently, genetic elements called SINEs (short interspersed elements) have emerged ...
Imagine a question-and-answer game played by two people who are not in the same place and not talking to each other. Round after round, one player asks a series of questions and accurately guesses the object the other is ...
Stanford University School of Medicine scientists successfully defeated a dangerous intestinal pathogen, Clostridium difficile, with a drug targeting its toxins rather than its life.
UC San Francisco researchers have successfully isolated human muscle stem cells and shown that the cells could robustly replicate and repair damaged muscles when grafted onto an injured site. The laboratory finding paves ...
A man suffering complete paralysis in both legs has regained the ability to walk again using electrical signals generated by his own brain. Unlike similar efforts that have seen paralyzed subjects walk again by using their own brainwaves to manually control robotic limbs, the researchers say this is the first time a person with complete paralysis in both legs due to spinal cord injury was able to walk again under their own power and demonstrates the potential for noninvasive therapies to restore control over paralyzed limbs.
