Emma
Evil Liberal Leftist
Indeed.
One of the articles I read this morning interviewed a cardiologist. He ticked off a long list of things that could cause cardiac arrest (but like you said, cardiac arrest doesn't mean anything, really). He mentioned long Q-T syndrome, which can be asymptomatic until someone is treated with a macrolide like a z-pack.
Whatever happened must have been rather immediate. Mom says she checked on her because she'd been in the bathroom for so long; there was no report she heard her call out for help.
Ah the Q-T prolongation question. Classic "pimp" question. Kind of like "red man syndrome" with Vanc or gingival hyperplasia with phenytoin. I think people love that question because macrolides are used so often.
Hey, look what I found!
Romano-Ward syndrome
Romano-Ward syndrome is an autosomal dominant form of LQTS that is not associated with deafness. The diagnosis is clinical and is now less commonly used in centres where genetic testing is available, in favour of the LQT1 to 10 scheme given above.
It is believed that the so-called early after-depolarizations (EADs) that are seen in LQTS are due to re-opening of L-type calcium channels during the plateau phase of the cardiac action potential. Since adrenergic stimulation can increase the activity of these channels, this is an explanation for why the risk of sudden death in individuals with LQTS is increased during increased adrenergic states (ie exercise, excitement) -- especially since repolarization is impaired. Normally during adrenergic states, repolarizing currents will also be enhanced to shorten the action potential. In the absence of this shortening and the presence of increased L-type calcium current, EADs may arise.
The diagnosis of LQTS is not easy since 2.5% of the healthy population have prolonged QT interval, and 1015% of LQTS patients have a normal QT interval.[3] A commonly used criterion to diagnose LQTS is the LQTS "diagnostic score" [4]. The score is calculated by assigning different points to various criteria (listed below). With 4 or more points the probability is high for LQTS, and with 1 point or less the probability is low. Two or 3 points indicates intermediate probability.
Physiological arrythmias!
You just wanted to use that phrase you made up